Structure-Based Virtual Screening of Tumor Necrosis Factor-α Inhibitors by Cheminformatics Approaches and Bio-Molecular Simulation

Tumor necrosis factor-α (TNF-α) is a drug target in rheumatoid arthritis and several other auto-immune disorders. TNF-α binds with TNF receptors (TNFR), located on the surface of several immunological cells to exert its effect. Hence, the use of inhibitors that can hinder the complex formation of TN...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biomolecules
Hauptverfasser: Halim, Sobia Ahsan, Sikandari, Almas Gul, Khan, Ajmal, Wadood, Abdul, Fatmi, Muhammad Qaiser, Csuk, René, Al-Harrasi, Ahmed
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926523/
https://ncbi.nlm.nih.gov/pubmed/33671607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020329
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge