Targeting Dengue Virus NS-3 Helicase by Ligand based Pharmacophore Modeling and Structure based Virtual Screening

Dengue fever is an emerging public health concern, with several million viral infections occur annually, for which no effective therapy currently exist. Non-structural protein 3 (NS-3) Helicase encoded by the dengue virus (DENV) is considered as a potential drug target to design new and effective dr...

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Udgivet i:Front Chem
Main Authors: Halim, Sobia A., Khan, Shanza, Khan, Ajmal, Wadood, Abdul, Mabood, Fazal, Hussain, Javid, Al-Harrasi, Ahmed
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671650/
https://ncbi.nlm.nih.gov/pubmed/29164104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2017.00088
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