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Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus
We performed a mutational analysis of the NS3 helicase of dengue virus to test insights gleaned from its crystal structure and identified four residues in the full-length protein that severely impaired either its RTPase and ATPase (Arg-457-458, Arg-460, Arg-463) or helicase (Ile-365, Arg-376) activi...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1488930/ https://ncbi.nlm.nih.gov/pubmed/16775356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02215-05 |
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