Targeting Dengue Virus NS-3 Helicase by Ligand based Pharmacophore Modeling and Structure based Virtual Screening

Dengue fever is an emerging public health concern, with several million viral infections occur annually, for which no effective therapy currently exist. Non-structural protein 3 (NS-3) Helicase encoded by the dengue virus (DENV) is considered as a potential drug target to design new and effective dr...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Halim, Sobia A., Khan, Shanza, Khan, Ajmal, Wadood, Abdul, Mabood, Fazal, Hussain, Javid, Al-Harrasi, Ahmed
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671650/
https://ncbi.nlm.nih.gov/pubmed/29164104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2017.00088
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