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MAPK signaling regulates c‐MYC for melanoma cell adaptation to asparagine restriction

Amino acid restriction is among promising potential cancer treatment strategies. However, cancer cells employ a multitude of mechanisms to mount resistance to amino acid restriction, which impede the latter’s clinical development. Here we show that MAPK signaling activation in asparagine‐restricted...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Pathria, Gaurav, Verma, Sachin, Yin, Jun, Scott, David A, Ronai, Ze’ev A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926261/
https://ncbi.nlm.nih.gov/pubmed/33554439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051436
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