H4K20me1 and H3K27me3 are concurrently loaded onto the inactive X chromosome but dispensable for inducing gene silencing

During X chromosome inactivation (XCI), in female placental mammals, gene silencing is initiated by the Xist long non‐coding RNA. Xist accumulation at the X leads to enrichment of specific chromatin marks, including PRC2‐dependent H3K27me3 and SETD8‐dependent H4K20me1. However, the dynamics of this...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Tjalsma, Sjoerd J D, Hori, Mayako, Sato, Yuko, Bousard, Aurelie, Ohi, Akito, Raposo, Ana Cláudia, Roensch, Julia, Le Saux, Agnes, Nogami, Jumpei, Maehara, Kazumitsu, Kujirai, Tomoya, Handa, Tetsuya, Bagés‐Arnal, Sandra, Ohkawa, Yasuyuki, Kurumizaka, Hitoshi, da Rocha, Simão Teixeira, Żylicz, Jan J, Kimura, Hiroshi, Heard, Edith
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926250/
https://ncbi.nlm.nih.gov/pubmed/33605056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051989
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker