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CUL2(LRR1), TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle
The eukaryotic replisome is disassembled in each cell cycle, dependent upon ubiquitylation of the CMG helicase. Studies of Saccharomyces cerevisiae, Caenorhabditis elegans and Xenopus laevis have revealed surprising evolutionary diversity in the ubiquitin ligases that control CMG ubiquitylation, but...
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| Publicado en: | EMBO Rep |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7926238/ https://ncbi.nlm.nih.gov/pubmed/33590678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202052164 |
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