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CUL2(LRR1), TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle

The eukaryotic replisome is disassembled in each cell cycle, dependent upon ubiquitylation of the CMG helicase. Studies of Saccharomyces cerevisiae, Caenorhabditis elegans and Xenopus laevis have revealed surprising evolutionary diversity in the ubiquitin ligases that control CMG ubiquitylation, but...

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Bibliografische gegevens
Gepubliceerd in:EMBO Rep
Hoofdauteurs: Villa, Fabrizio, Fujisawa, Ryo, Ainsworth, Johanna, Nishimura, Kohei, Lie‐A‐Ling, Michael, Lacaud, Georges, Labib, Karim PM
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926238/
https://ncbi.nlm.nih.gov/pubmed/33590678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202052164
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