MITOL promotes cell survival by degrading Parkin during mitophagy

Parkin promotes cell survival by removing damaged mitochondria via mitophagy. However, although some studies have suggested that Parkin induces cell death, the regulatory mechanism underlying the dual role of Parkin remains unknown. Herein, we report that mitochondrial ubiquitin ligase (MITOL/MARCH5...

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Publicado en:EMBO Rep
Main Authors: Shiiba, Isshin, Takeda, Keisuke, Nagashima, Shun, Ito, Naoki, Tokuyama, Takeshi, Yamashita, Shun‐Ichi, Kanki, Tomotake, Komatsu, Toru, Urano, Yasuteru, Fujikawa, Yuuta, Inatome, Ryoko, Yanagi, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926225/
https://ncbi.nlm.nih.gov/pubmed/33565245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949097
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