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MITOL promotes cell survival by degrading Parkin during mitophagy

Parkin promotes cell survival by removing damaged mitochondria via mitophagy. However, although some studies have suggested that Parkin induces cell death, the regulatory mechanism underlying the dual role of Parkin remains unknown. Herein, we report that mitochondrial ubiquitin ligase (MITOL/MARCH5...

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書目詳細資料
發表在:EMBO Rep
Main Authors: Shiiba, Isshin, Takeda, Keisuke, Nagashima, Shun, Ito, Naoki, Tokuyama, Takeshi, Yamashita, Shun‐Ichi, Kanki, Tomotake, Komatsu, Toru, Urano, Yasuteru, Fujikawa, Yuuta, Inatome, Ryoko, Yanagi, Shigeru
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926225/
https://ncbi.nlm.nih.gov/pubmed/33565245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949097
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