MITOL promotes cell survival by degrading Parkin during mitophagy

Parkin promotes cell survival by removing damaged mitochondria via mitophagy. However, although some studies have suggested that Parkin induces cell death, the regulatory mechanism underlying the dual role of Parkin remains unknown. Herein, we report that mitochondrial ubiquitin ligase (MITOL/MARCH5...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Principais autores: Shiiba, Isshin, Takeda, Keisuke, Nagashima, Shun, Ito, Naoki, Tokuyama, Takeshi, Yamashita, Shun‐Ichi, Kanki, Tomotake, Komatsu, Toru, Urano, Yasuteru, Fujikawa, Yuuta, Inatome, Ryoko, Yanagi, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926225/
https://ncbi.nlm.nih.gov/pubmed/33565245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949097
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