MITOL promotes cell survival by degrading Parkin during mitophagy

Parkin promotes cell survival by removing damaged mitochondria via mitophagy. However, although some studies have suggested that Parkin induces cell death, the regulatory mechanism underlying the dual role of Parkin remains unknown. Herein, we report that mitochondrial ubiquitin ligase (MITOL/MARCH5...

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Gepubliceerd in:EMBO Rep
Hoofdauteurs: Shiiba, Isshin, Takeda, Keisuke, Nagashima, Shun, Ito, Naoki, Tokuyama, Takeshi, Yamashita, Shun‐Ichi, Kanki, Tomotake, Komatsu, Toru, Urano, Yasuteru, Fujikawa, Yuuta, Inatome, Ryoko, Yanagi, Shigeru
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2021
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926225/
https://ncbi.nlm.nih.gov/pubmed/33565245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949097
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