Novel Oncolytic Herpes Simplex Virus 1 VC2 Promotes Long-Lasting, Systemic Anti-melanoma Tumor Immune Responses and Increased Survival in an Immunocompetent B16F10-Derived Mouse Melanoma Model

Oncolytic virotherapy (OVT) is now understood to be an immunotherapy that uses viral infection to liberate tumor antigens in an immunogenic context to promote the development of antitumor immune responses. The only currently FDA-approved oncolytic virotherapy, T-Vec, is a modified type 1 herpes simp...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Uche, Ifeanyi Kingsley, Fowlkes, Natalie, Vu, Luan, Watanabe, Tatiane, Carossino, Mariano, Nabi, Rafiq, del Piero, Fabio, Rudd, Jared S., Kousoulas, Konstantin G., Rider, Paul J. F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2021
Pynciau:
Cellular Response to Infection
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925097/
https://ncbi.nlm.nih.gov/pubmed/33177208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01359-20
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