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Anti-viral immunity in the tumor microenvironment: implications for the rational design of herpes simplex virus type 1 oncolytic virotherapy

PURPOSE OF REVIEW: The design of novel herpes simplex type I (HSV-1)-derived oncolytic virotherapies is a balancing act between safety, immunogenicity and replicative potential. We have undertaken this review to better understand how these considerations can be incorporated into rational approaches...

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Bibliografiska uppgifter
I publikationen:Curr Clin Microbiol Rep
Huvudupphovsmän: Rider, Paul J. F., Uche, Ifeanyi K., Sweeny, Larissa, Kousoulas, Konstantin G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7748056/
https://ncbi.nlm.nih.gov/pubmed/33344108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40588-019-00134-3
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