Bicelles Rich in both Sphingolipids and Cholesterol and Their Use in Studies of Membrane Proteins

How the distinctive lipid composition of mammalian plasma membranes impacts membrane protein structure is largely unexplored, partly because of the dearth of isotropic model membrane systems that contain abundant sphingolipids and cholesterol. This gap is addressed by showing that sphingomyelin and...

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Библиографические подробности
Опубликовано в: :J Am Chem Soc
Главные авторы: Hutchison, James M., Shih, Kuo-Chih, Scheidt, Holger A., Fantin, Sarah M., Parson, Kristine F., Pantelopulos, George A., Harrington, Haley R., Mittendorf, Kathleen F., Qian, Shuo, Stein, Richard A., Collier, Scott E., Chambers, Melissa G., Katsaras, John, Voehler, Markus W., Ruotolo, Brandon T., Huster, Daniel, McFeeters, Robert L., Straub, John E., Nieh, Mu-Ping, Sanders, Charles R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924963/
https://ncbi.nlm.nih.gov/pubmed/32575981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c04669
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