Bicelles Rich in both Sphingolipids and Cholesterol and Their Use in Studies of Membrane Proteins

How the distinctive lipid composition of mammalian plasma membranes impacts membrane protein structure is largely unexplored, partly because of the dearth of isotropic model membrane systems that contain abundant sphingolipids and cholesterol. This gap is addressed by showing that sphingomyelin and...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Hutchison, James M., Shih, Kuo-Chih, Scheidt, Holger A., Fantin, Sarah M., Parson, Kristine F., Pantelopulos, George A., Harrington, Haley R., Mittendorf, Kathleen F., Qian, Shuo, Stein, Richard A., Collier, Scott E., Chambers, Melissa G., Katsaras, John, Voehler, Markus W., Ruotolo, Brandon T., Huster, Daniel, McFeeters, Robert L., Straub, John E., Nieh, Mu-Ping, Sanders, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924963/
https://ncbi.nlm.nih.gov/pubmed/32575981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c04669
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