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Membrane binding and homodimerization of Atg16 via two distinct protein regions is essential for autophagy in yeast
Macroautophagy is a bulk degradation mechanism in eukaryotic cells. Efficiency of an essential step of this process in yeast, Atg8 lipidation, relies on the presence of Atg16, a subunit of the Atg12–Atg5-Atg16 complex acting as the E3-like enzyme in the ubiquitination-like reaction. A current view o...
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| Vydáno v: | J Mol Biol |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7924733/ https://ncbi.nlm.nih.gov/pubmed/33484718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2021.166809 |
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