Genome-wide association study of rate of cognitive decline in Alzheimer’s Disease patients identifies novel genes and pathways

INTRODUCTION: Variability exists in the disease trajectories of Alzheimer’s disease (AD) patients. We performed a genome-wide association study to examine rate-of-cognitive-decline (ROD) in AD patients. METHODS: We tested for interactions between genetic variants and time since diagnosis to predict...

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Bibliografiset tiedot
Julkaisussa:Alzheimers Dement
Päätekijät: Sherva, Richard, Gross, Alden, Mukherjee, Shubhabrata, Koesterer, Ryan, Amouyel, Philippe, Bellenguez, Celine, Dufouil, Carole, Bennett, David A., Chibnik, Lori, Cruchaga, Carlos, del-Aguila, Jorge, Farrer, Lindsay A., Mayeux, Richard, Munsie, Leanne, Winslow, Ashley, Newhouse, Stephen, Saykin, Andrew J., Kauwe, John S.K., Crane, Paul K., Green, Robert C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924136/
https://ncbi.nlm.nih.gov/pubmed/32573913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12106
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