Genetically Predicted Body Mass Index and Alzheimer’s Disease Related Phenotypes in Three Large Samples: Mendelian Randomization Analyses

Observational research shows that higher body mass index (BMI) increases Alzheimer’s disease (AD) risk, but it is unclear whether this association is causal. We applied genetic variants that predict BMI in Mendelian Randomization analyses, an approach that is not biased by reverse causation or confo...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Mukherjee, Shubhabrata, Walter, Stefan, Kauwe, John S.K., Saykin, Andrew J., Bennett, David A., Larson, Eric B., Crane, Paul K., Glymour, M. Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676945/
https://ncbi.nlm.nih.gov/pubmed/26079416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2015.05.015
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