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Modulation of α1β3γ2 GABA(A) receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helix
Tethered photoswitches are molecules with two photo-dependent isomeric forms, each with different actions on their biological targets. They include reactive chemical groups capable of covalently binding to their target. Our aim was to develop a β-subunit-tethered propofol photoswitch (MAP20), as a t...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7923644/ https://ncbi.nlm.nih.gov/pubmed/33593898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008178118 |
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