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Identification of an Inhibitory Alcohol Binding Site in GABA(A) ρ1 Receptors
Alcohols inhibit γ-aminobutyric acid type A ρ1 receptor function. After introducing mutations in several positions of the second transmembrane helix in ρ1, we studied the effects of ethanol and hexanol on GABA responses using two-electrode voltage clamp electrophysiology in Xenopus laevis oocytes. T...
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| Publicado no: | ACS Chem Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4934417/ https://ncbi.nlm.nih.gov/pubmed/26571107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00246 |
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