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A Transmembrane Amino Acid in the GABA(A) Receptor β(2) Subunit Critical for the Actions of Alcohols and Anesthetics

Alcohols and inhaled anesthetics enhance the function of GABA(A) receptors containing α, β, and γ subunits. Molecular analysis has focused on the role of the α subunits; however, there is evidence that the β subunits may also be important. The goal of our study was to determine whether Asn265, which...

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Autori principali: McCracken, Mandy L., Borghese, Cecilia M., Trudell, James R., Harris, R. Adron
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993559/
https://ncbi.nlm.nih.gov/pubmed/20826568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.170472
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