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A Transmembrane Amino Acid in the GABA(A) Receptor β(2) Subunit Critical for the Actions of Alcohols and Anesthetics

Alcohols and inhaled anesthetics enhance the function of GABA(A) receptors containing α, β, and γ subunits. Molecular analysis has focused on the role of the α subunits; however, there is evidence that the β subunits may also be important. The goal of our study was to determine whether Asn265, which...

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Bibliographic Details
Main Authors: McCracken, Mandy L., Borghese, Cecilia M., Trudell, James R., Harris, R. Adron
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993559/
https://ncbi.nlm.nih.gov/pubmed/20826568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.170472
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