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Transiently structured head domains control intermediate filament assembly

Low complexity (LC) head domains 92 and 108 residues in length are, respectively, required for assembly of neurofilament light (NFL) and desmin intermediate filaments (IFs). As studied in isolation, these IF head domains interconvert between states of conformational disorder and labile, β-strand–enr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhou, Xiaoming, Lin, Yi, Kato, Masato, Mori, Eiichiro, Liszczak, Glen, Sutherland, Lillian, Sysoev, Vasiliy O., Murray, Dylan T., Tycko, Robert, McKnight, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923618/
https://ncbi.nlm.nih.gov/pubmed/33593918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022121118
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