Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains

Polymerization and phase separation of proteins containing low-complexity (LC) domains are important factors in gene expression, mRNA processing and trafficking, and localization of translation. We have used solid state nuclear magnetic resonance methods to characterize the molecular structure of se...

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Bibliografiset tiedot
Julkaisussa:Cell
Päätekijät: Murray, Dylan T., Kato, Masato, Lin, Yi, Thurber, Kent R., Hung, Ivan, McKnight, Steven L., Tycko, Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650524/
https://ncbi.nlm.nih.gov/pubmed/28942918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.08.048
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