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Regulation of pyruvate dehydrogenase complex related to lactate switch in CHO cells

The metabolism of Chinese hamster ovary (CHO) cell lines is typically characterized by high rates of aerobic glycolysis with increased lactate formation, known as the ”Warburg” effect. Although this metabolic state can switch to lactate consumption, the involved regulations of the central metabolism...

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Dettagli Bibliografici
Pubblicato in:Eng Life Sci
Autori principali: Möller, Johannes, Bhat, Krathika, Guhl, Lotta, Pörtner, Ralf, Jandt, Uwe, Zeng, An‐Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923601/
https://ncbi.nlm.nih.gov/pubmed/33716610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elsc.202000037
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