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Regulation of pyruvate dehydrogenase complex related to lactate switch in CHO cells

The metabolism of Chinese hamster ovary (CHO) cell lines is typically characterized by high rates of aerobic glycolysis with increased lactate formation, known as the ”Warburg” effect. Although this metabolic state can switch to lactate consumption, the involved regulations of the central metabolism...

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Detalhes bibliográficos
Publicado no:Eng Life Sci
Main Authors: Möller, Johannes, Bhat, Krathika, Guhl, Lotta, Pörtner, Ralf, Jandt, Uwe, Zeng, An‐Ping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923601/
https://ncbi.nlm.nih.gov/pubmed/33716610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elsc.202000037
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