Novel methylated DNA markers accurately discriminate Lynch syndrome associated colorectal neoplasia

AIM: Acquired molecular changes in Lynch syndrome (LS) colorectal tumors have been largely unstudied. We identified methylated DNA markers (MDMs) for discrimination of colorectal neoplasia in LS and determined if these MDMs were comparably discriminant in sporadic patients. PATIENTS & METHODS: F...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Epigenomics
Egile Nagusiak: Ballester, Veroushka, Taylor, William R, Slettedahl, Seth W, Mahoney, Douglas W, Yab, Tracy C, Sinicrope, Frank A, Boland, Clement R, Lidgard, Graham P, Cruz-Correa, Marcia R, Smyrk, Thomas C, Boardman, Lisa A, Ahlquist, David A, Kisiel, John B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Future Medicine Ltd 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923255/
https://ncbi.nlm.nih.gov/pubmed/33350853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2020-0132
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