Novel methylated DNA markers accurately discriminate Lynch syndrome associated colorectal neoplasia

AIM: Acquired molecular changes in Lynch syndrome (LS) colorectal tumors have been largely unstudied. We identified methylated DNA markers (MDMs) for discrimination of colorectal neoplasia in LS and determined if these MDMs were comparably discriminant in sporadic patients. PATIENTS & METHODS: F...

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Vydáno v:Epigenomics
Hlavní autoři: Ballester, Veroushka, Taylor, William R, Slettedahl, Seth W, Mahoney, Douglas W, Yab, Tracy C, Sinicrope, Frank A, Boland, Clement R, Lidgard, Graham P, Cruz-Correa, Marcia R, Smyrk, Thomas C, Boardman, Lisa A, Ahlquist, David A, Kisiel, John B
Médium: Artigo
Jazyk:Inglês
Vydáno: Future Medicine Ltd 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923255/
https://ncbi.nlm.nih.gov/pubmed/33350853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2020-0132
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