Novel methylated DNA markers accurately discriminate Lynch syndrome associated colorectal neoplasia

AIM: Acquired molecular changes in Lynch syndrome (LS) colorectal tumors have been largely unstudied. We identified methylated DNA markers (MDMs) for discrimination of colorectal neoplasia in LS and determined if these MDMs were comparably discriminant in sporadic patients. PATIENTS & METHODS: F...

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Bibliografske podrobnosti
izdano v:Epigenomics
Main Authors: Ballester, Veroushka, Taylor, William R, Slettedahl, Seth W, Mahoney, Douglas W, Yab, Tracy C, Sinicrope, Frank A, Boland, Clement R, Lidgard, Graham P, Cruz-Correa, Marcia R, Smyrk, Thomas C, Boardman, Lisa A, Ahlquist, David A, Kisiel, John B
Format: Artigo
Jezik:Inglês
Izdano: Future Medicine Ltd 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923255/
https://ncbi.nlm.nih.gov/pubmed/33350853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2020-0132
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