Novel methylated DNA markers accurately discriminate Lynch syndrome associated colorectal neoplasia

AIM: Acquired molecular changes in Lynch syndrome (LS) colorectal tumors have been largely unstudied. We identified methylated DNA markers (MDMs) for discrimination of colorectal neoplasia in LS and determined if these MDMs were comparably discriminant in sporadic patients. PATIENTS & METHODS: F...

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Detalles Bibliográficos
Publicado en:Epigenomics
Main Authors: Ballester, Veroushka, Taylor, William R, Slettedahl, Seth W, Mahoney, Douglas W, Yab, Tracy C, Sinicrope, Frank A, Boland, Clement R, Lidgard, Graham P, Cruz-Correa, Marcia R, Smyrk, Thomas C, Boardman, Lisa A, Ahlquist, David A, Kisiel, John B
Formato: Artigo
Idioma:Inglês
Publicado: Future Medicine Ltd 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923255/
https://ncbi.nlm.nih.gov/pubmed/33350853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2020-0132
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