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Multivalent Rubber-like RNA Nanoparticles for Targeted Co-delivery of Paclitaxel and MiRNA to Silence the Drug Efflux Transporter and Liver Cancer Drug Resistance

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Analogous to the border customs, liver mainly functions as a filter to detoxify chemicals and metabolite administered orally or intravenously. Besides, liver cancer cells overexpress the drug exporters which...

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Podrobná bibliografie
Vydáno v:J Control Release
Hlavní autoři: Wang, Hongzhi, Ellipilli, Satheesh, Lee, Wen-Jui, Li, Xin, Vieweger, Mario, Ho, Yuan-Soon, Guo, Peixuan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923242/
https://ncbi.nlm.nih.gov/pubmed/33316298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.12.007
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