Human Epidermal Growth Factor Receptor-3 Expression Is Regulated at Transcriptional Level in Breast Cancer Settings by Junctional Adhesion Molecule-A via a Pathway Involving Beta-Catenin and FOXA1

SIMPLE SUMMARY: Signaling from the human epidermal growth factor receptor (HER) family of proteins increases in many cancers, including breast. HER2-high breast cancers are successfully treated with anti-HER2 therapies, but these drugs are limited by the fact that patients frequently develop resista...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Cruz, Rodrigo G. B., Madden, Stephen F., Richards, Cathy E., Vellanki, Sri HariKrishna, Jahns, Hanne, Hudson, Lance, Fay, Joanna, O’Farrell, Naoimh, Sheehan, Katherine, Jirström, Karin, Brennan, Kieran, Hopkins, Ann M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922773/
https://ncbi.nlm.nih.gov/pubmed/33669586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040871
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