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TET3 regulates DNA hydroxymethylation of neuroprotective genes following focal ischemia
The 5-hydroxymethylcytosine (5hmC) epigenetic modification is highly enriched in the CNS and a critical modulator of neuronal function and development. We found that cortical 5hmC was enhanced from 5 min to three days of reperfusion following focal ischemia in adult mice. Blockade of the 5hmC-produc...
Gardado en:
| Publicado en: | J Cereb Blood Flow Metab |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
SAGE Publications
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7922754/ https://ncbi.nlm.nih.gov/pubmed/32380888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X20912965 |
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