Increased cerebral protein ISGylation after focal ischemia is neuroprotective

Addition of a small peptide called ISG15 is known as ISGylation, which is an ubiquitin (ub)-like posttranslational modification. We currently show that focal ischemia induced by transient middle cerebral artery occlusion (MCAO) in adult mice significantly induces cortical protein ISGylation between...

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Autori principali: Nakka, Venkata P, Lang, Bradley T, Lenschow, Deborah J, Zhang, Dong-Er, Dempsey, Robert J, Vemuganti, Raghu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323186/
https://ncbi.nlm.nih.gov/pubmed/21847135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.103
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