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Induction of DNA hydroxymethylation protects the brain after stroke

BACKGROUND AND PURPOSE: Epigenetics play a significant role in brain pathologies. We currently evaluated the role of a recently discovered CNS-enriched epigenetic modification known as 5-hydroxymethylcytosine (5hmC) in regulating transcriptomic and pathogenic mechanisms following focal ischemic inju...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Morris-Blanco, Kahlilia C., Kim, TaeHee, Lopez, Mary S., Bertogliat, Mario J., Chelluboina, Bharath, Vemuganti, Raghu
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710106/
https://ncbi.nlm.nih.gov/pubmed/31327315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.119.025665
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