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Estimating Copy-Number Proportions: The Comeback of Sanger Sequencing

Determination of the relative copy numbers of mixed molecular species in nucleic acid samples is often the objective of biological experiments, including Single-Nucleotide Polymorphism (SNP), indel and gene copy-number characterization, and quantification of CRISPR-Cas9 base editing, cytosine methyl...

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Pubblicato in:Genes (Basel)
Autore principale: Seroussi, Eyal
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922598/
https://ncbi.nlm.nih.gov/pubmed/33671263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12020283
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