Estimation of Copy Number Alterations from Exome Sequencing Data

Exome sequencing constitutes an important technology for the study of human hereditary diseases and cancer. However, the ability of this approach to identify copy number alterations in primary tumor samples has not been fully addressed. Here we show that somatic copy number alterations can be reliab...

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Bibliografiske detaljer
Main Authors: Valdés-Mas, Rafael, Bea, Silvia, Puente, Diana A., López-Otín, Carlos, Puente, Xose S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526607/
https://ncbi.nlm.nih.gov/pubmed/23284693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051422
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