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Estimation of Copy Number Alterations from Exome Sequencing Data

Exome sequencing constitutes an important technology for the study of human hereditary diseases and cancer. However, the ability of this approach to identify copy number alterations in primary tumor samples has not been fully addressed. Here we show that somatic copy number alterations can be reliab...

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Détails bibliographiques
Auteurs principaux: Valdés-Mas, Rafael, Bea, Silvia, Puente, Diana A., López-Otín, Carlos, Puente, Xose S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526607/
https://ncbi.nlm.nih.gov/pubmed/23284693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051422
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