Patient Derived Xenografts for Genome-Driven Therapy of Osteosarcoma

Osteosarcoma (OS) is a rare malignant primary tumor of mesenchymal origin affecting bone. It is characterized by a complex genotype, mainly due to the high frequency of chromothripsis, which leads to multiple somatic copy number alterations and structural rearrangements. Any effort to design genome-...

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Bibliographic Details
Published in:Cells
Main Authors: Landuzzi, Lorena, Manara, Maria Cristina, Lollini, Pier-Luigi, Scotlandi, Katia
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922432/
https://ncbi.nlm.nih.gov/pubmed/33671173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020416
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