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Pharmacodynamics of Ceftibuten: An Assessment of an Oral Cephalosporin against Enterobacterales in a Neutropenic Murine Thigh Model

Efforts to develop and pair novel oral β-lactamase inhibitors with existing β-lactam agents to treat extended spectrum β-lactamase (ESBL) and carbapenemase-producing Enterobacterales are gaining ground. Ceftibuten is an oral third-generation cephalosporin capable of achieving high urine concentratio...

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Bibliographic Details
Published in:Antibiotics (Basel)
Main Authors: Lasko, Maxwell J., Asempa, Tomefa E., Nicolau, David P.
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922365/
https://ncbi.nlm.nih.gov/pubmed/33669512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics10020201
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