Cellular Fitness Phenotypes of Cancer Target Genes from Oncobiology to Cancer Therapeutics

To define the growing significance of cellular targets and/or effectors of cancer drugs, we examined the fitness dependency of cellular targets and effectors of cancer drug targets across human cancer cells from 19 cancer types. We observed that the deletion of 35 out of 47 cellular effectors and/or...

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Dades bibliogràfiques
Publicat a:Cells
Autors principals: George, Bijesh, Pillai, P. Mukundan, Paul, Aswathy Mary, Amjesh, Revikumar, Leitzel, Kim, Ali, Suhail M., Sandiford, Oleta, Lipton, Allan, Rameshwar, Pranela, Hortobagyi, Gabriel N., Pillai, Madhavan Radhakrishna, Kumar, Rakesh
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921985/
https://ncbi.nlm.nih.gov/pubmed/33670680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020433
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