Cellular Fitness Phenotypes of Cancer Target Genes from Oncobiology to Cancer Therapeutics

To define the growing significance of cellular targets and/or effectors of cancer drugs, we examined the fitness dependency of cellular targets and effectors of cancer drug targets across human cancer cells from 19 cancer types. We observed that the deletion of 35 out of 47 cellular effectors and/or...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: George, Bijesh, Pillai, P. Mukundan, Paul, Aswathy Mary, Amjesh, Revikumar, Leitzel, Kim, Ali, Suhail M., Sandiford, Oleta, Lipton, Allan, Rameshwar, Pranela, Hortobagyi, Gabriel N., Pillai, Madhavan Radhakrishna, Kumar, Rakesh
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921985/
https://ncbi.nlm.nih.gov/pubmed/33670680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020433
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