Cellular Fitness Phenotypes of Cancer Target Genes from Oncobiology to Cancer Therapeutics

To define the growing significance of cellular targets and/or effectors of cancer drugs, we examined the fitness dependency of cellular targets and effectors of cancer drug targets across human cancer cells from 19 cancer types. We observed that the deletion of 35 out of 47 cellular effectors and/or...

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Pubblicato in:Cells
Autori principali: George, Bijesh, Pillai, P. Mukundan, Paul, Aswathy Mary, Amjesh, Revikumar, Leitzel, Kim, Ali, Suhail M., Sandiford, Oleta, Lipton, Allan, Rameshwar, Pranela, Hortobagyi, Gabriel N., Pillai, Madhavan Radhakrishna, Kumar, Rakesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921985/
https://ncbi.nlm.nih.gov/pubmed/33670680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020433
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