Cellular Fitness Phenotypes of Cancer Target Genes from Oncobiology to Cancer Therapeutics

To define the growing significance of cellular targets and/or effectors of cancer drugs, we examined the fitness dependency of cellular targets and effectors of cancer drug targets across human cancer cells from 19 cancer types. We observed that the deletion of 35 out of 47 cellular effectors and/or...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cells
Auteurs principaux: George, Bijesh, Pillai, P. Mukundan, Paul, Aswathy Mary, Amjesh, Revikumar, Leitzel, Kim, Ali, Suhail M., Sandiford, Oleta, Lipton, Allan, Rameshwar, Pranela, Hortobagyi, Gabriel N., Pillai, Madhavan Radhakrishna, Kumar, Rakesh
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921985/
https://ncbi.nlm.nih.gov/pubmed/33670680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020433
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