A carregar...
Phosphorylation-dependent regulation of SPOP by LIMK2 promotes castration-resistant prostate cancer
BACKGROUND: SPOP, an E3 ubiquitin ligase adaptor, can act either as a tumour suppressor or a tumour promoter. In prostate cancer (PCa), it inhibits tumorigenesis by degrading several oncogenic substrates. SPOP is the most altered gene in PCa (~15%), which renders it ineffective, promoting cancer. Th...
Na minha lista:
| Publicado no: | Br J Cancer |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7921662/ https://ncbi.nlm.nih.gov/pubmed/33311589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01197-6 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|