Aurora Kinase A-YBX1 Synergy Fuels Aggressive Oncogenic Phenotypes and Chemoresistance in Castration-Resistant Prostate Cancer

Multifunctional protein YBX1 upregulation promotes castration-resistant prostate cancer (CRPC). However, YBX1 protein abundance, but not its DNA status or mRNA levels, predicts CRPC recurrence, although the mechanism remains unknown. Similarly, the mechanism by which YBX1 regulates androgen receptor...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Nikhil, Kumar, Raza, Asif, Haymour, Hanan S., Flueckiger, Benjamin V., Chu, Jiachong, Shah, Kavita
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140108/
https://ncbi.nlm.nih.gov/pubmed/32178290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030660
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