Loading...
Conformational states dynamically populated by a kinase determine its function
Protein kinases intrinsically sample a number of conformational states with distinct catalytic and binding activities. We used nuclear magnetic resonance spectroscopy to describe in atomic-level detail how Abl kinase interconverts between an active and two discrete inactive structures. Extensive dif...
Na minha lista:
| Udgivet i: | Science |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7920495/ https://ncbi.nlm.nih.gov/pubmed/33004676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc2754 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|