Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex

Nuclear Argonaute proteins, guided by their bound small RNAs to nascent target transcripts, mediate cotranscriptional silencing of transposons and repetitive genomic loci through heterochromatin formation. The molecular mechanisms involved in this process are incompletely understood. Here, we show t...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Schnabl, Jakob, Wang, Juncheng, Hohmann, Ulrich, Gehre, Maja, Batki, Julia, Andreev, Veselin I., Purkhauser, Kim, Fasching, Nina, Duchek, Peter, Novatchkova, Maria, Mechtler, Karl, Plaschka, Clemens, Patel, Dinshaw J., Brennecke, Julius
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919418/
https://ncbi.nlm.nih.gov/pubmed/33574069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.347989.120
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