Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex

Nuclear Argonaute proteins, guided by their bound small RNAs to nascent target transcripts, mediate cotranscriptional silencing of transposons and repetitive genomic loci through heterochromatin formation. The molecular mechanisms involved in this process are incompletely understood. Here, we show t...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Schnabl, Jakob, Wang, Juncheng, Hohmann, Ulrich, Gehre, Maja, Batki, Julia, Andreev, Veselin I., Purkhauser, Kim, Fasching, Nina, Duchek, Peter, Novatchkova, Maria, Mechtler, Karl, Plaschka, Clemens, Patel, Dinshaw J., Brennecke, Julius
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919418/
https://ncbi.nlm.nih.gov/pubmed/33574069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.347989.120
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