Circadian hepatocyte clocks keep synchrony in the absence of a master pacemaker in the suprachiasmatic nucleus or other extrahepatic clocks

It has been assumed that the suprachiasmatic nucleus (SCN) synchronizes peripheral circadian oscillators. However, this has never been convincingly shown, since biochemical time series experiments are not feasible in behaviorally arrhythmic animals. By using long-term bioluminescence recording in fr...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Sinturel, Flore, Gos, Pascal, Petrenko, Volodymyr, Hagedorn, Claudia, Kreppel, Florian, Storch, Kai-Florian, Knutti, Darko, Liani, Andre, Weitz, Charles, Emmenegger, Yann, Franken, Paul, Bonacina, Luigi, Dibner, Charna, Schibler, Ueli
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2021
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919413/
https://ncbi.nlm.nih.gov/pubmed/33602874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.346460.120
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