Circadian hepatocyte clocks keep synchrony in the absence of a master pacemaker in the suprachiasmatic nucleus or other extrahepatic clocks

It has been assumed that the suprachiasmatic nucleus (SCN) synchronizes peripheral circadian oscillators. However, this has never been convincingly shown, since biochemical time series experiments are not feasible in behaviorally arrhythmic animals. By using long-term bioluminescence recording in fr...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Sinturel, Flore, Gos, Pascal, Petrenko, Volodymyr, Hagedorn, Claudia, Kreppel, Florian, Storch, Kai-Florian, Knutti, Darko, Liani, Andre, Weitz, Charles, Emmenegger, Yann, Franken, Paul, Bonacina, Luigi, Dibner, Charna, Schibler, Ueli
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919413/
https://ncbi.nlm.nih.gov/pubmed/33602874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.346460.120
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