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Apigenin Attenuates Acetaminophen-Induced Hepatotoxicity by Activating AMP-Activated Protein Kinase/Carnitine Palmitoyltransferase I Pathway
Overuse of acetaminophen (APAP) is a major cause of drug-induced liver failure at the clinics. Apigenin (API) is a natural flavonoid derived from Matricaria chamomilla. The aim of the present study was to investigate the amelioration function of API in APAP-induced hepatotoxicity both in vitro and i...
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Publié dans: | Front Pharmacol |
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Auteurs principaux: | , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Frontiers Media S.A.
2020
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7919381/ https://ncbi.nlm.nih.gov/pubmed/33658919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.549057 |
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