Apigenin Prevents Acetaminophen-Induced Liver Injury by Activating the SIRT1 Pathway

Acetaminophen (APAP) overdose is the main cause of acute liver failure. Apigenin (API) is a natural dietary flavonol with high antioxidant capacity. Herein, we investigated protection by API against APAP-induced liver injury in mice, and explored the potential mechanism. Cell viability assays and mi...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhao, Licong, Zhang, Jiaqi, Hu, Cheng, Wang, Tao, Lu, Juan, Wu, Chenqu, Chen, Long, Jin, Mingming, Ji, Guang, Cao, Qin, Jiang, Yuanye
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212374/
https://ncbi.nlm.nih.gov/pubmed/32425778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00514
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