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Preparation and Bioevaluation of Novel (99m)Tc-Labeled Complexes with a 2-Nitroimidazole HYNIC Derivative for Imaging Tumor Hypoxia
To develop novel (99m)Tc-labeled single-photon emission computed tomography (SPECT) radiotracers for imaging hypoxia, a novel HYNICNM ligand (6-hydrazinonicotinamide (HYNIC) 2-nitroimidazole derivative) was designed and synthesized. It was radiolabeled with technetium-99m using tricine/trisodium tri...
Enregistré dans:
| Publié dans: | Pharmaceuticals (Basel) |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7919024/ https://ncbi.nlm.nih.gov/pubmed/33671923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14020158 |
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