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Novel (99m)Tc labelled complexes with 2-nitroimidazole isocyanide: design, synthesis and evaluation as potential tumor hypoxia imaging agents
Radiolabelled 2-nitroimidazoles have been used for imaging hypoxia. With the aim of developing novel (99m)Tc radiotracers for imaging hypoxia, four novel 2-nitroimidazole isocyanide derivatives (2a, 2b, 2c, and 2d) were synthesized and radiolabelling was carried out for preparing their corresponding...
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| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072354/ https://ncbi.nlm.nih.gov/pubmed/30108988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00146d |
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