PF-3845, a Fatty Acid Amide Hydrolase Inhibitor, Directly Suppresses Osteoclastogenesis through ERK and NF-κB Pathways In Vitro and Alveolar Bone Loss In Vivo

Alveolar bone loss, the major feature of periodontitis, results from the activation of osteoclasts, which can consequently cause teeth to become loose and fall out; the development of drugs capable of suppressing excessive osteoclast differentiation and function is beneficial for periodontal disease...

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Publicado no:Int J Mol Sci
Main Authors: Ihn, Hye-Jung, Kim, Yi-Seul, Lim, Soomin, Bae, Jong-Sup, Jung, Jae-Chang, Kim, Yeo-Hyang, Park, Jin-Woo, Wang, Zhao, Koh, Jeong-Tae, Bae, Yong-Chul, Baek, Moon-Chang, Park, Eui-Kyun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919013/
https://ncbi.nlm.nih.gov/pubmed/33671948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041915
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